Many of the side effects of hormone treatment are related to the lack of normal levels of male hormone within your body and occur whether you choose surgery or medications.
Some men notice an alteration of their body hair, such that it is a different texture and may grow again on previously quite bald areas. Tiredness is a common complaint as well.
After hormone therapy, about 90% of men have reduced sexual desire and in some cases, impotence. Over half of men have hot flashes (sudden rushes of body heat) after surgery, but these may go away with time.
Side effects of one hormone treatment, known as luteinizing hormone-releasing hormone (LHRH) agonists include reduced or absent sexual desire, impotence, and hot flashes. Some men also have breast tenderness and growth of breast tissue.
Breast growth usually occurs in men who take estrogen therapy. Using LHRH agonists over a long period of time can also cause osteoporosis (weakening of bones), fatigue, muscle wasting, and change in fat distribution.
When first given, these medicines can cause a temporary rise in testosterone levels, which can cause pain at tumor sites, especially if the cancer has already spread to bone. To prevent this, a short course of anti-androgens (at least 7 days) may be given when the LHRH agonist is first started.
Side effects of anti-androgens in patients with LHRH agonists are usually not serious or common, but may include nausea, diarrhea, tiredness, liver disease, and the growth of breast tissue, especially with prolonged use.
These side effects can vary in intensity and depends on treatment options and other intangible factors such as health, fitness. Before commencing on hormonal therapy, it is helpful to discuss the possibility of side effects with your wife or partner.
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